This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects.
Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome oxidase deficiency; use of tissue culture in the diagnosis of mitochondrial disease; and advances in mitochondrial genetics.
This publication is a good source for clinicians and students concerned with the defective mitochondrial function.
- ISBN: 9781483193694 |
- Hardcover: 264 pages |
- Publisher: Elsevier Science |
- Publication date: Oct 22, 2013 |
- Language: English |
- Format: Ebook